Regenerative medicine can reverse knee cartilage injuries

What exactly is regenerative medicine and how does it work in trauma injuries?

Regenerative medicine is based on treatment that takes advantage of the self-repair capacity of the human body itself to regenerate tissues from progenitor cells (stem cells), being the only cells that have the potential to become multiple cells of different lineages (chondrocytes). , osteoblasts, adipocytes, etc.)

What types of cartilage injuries can be treated with regenerative medicine?

All injuries that cause loss of joint cartilage, either due to degenerative processes such as vascular changes, overuse or due to trauma.

In other words, does it apply to both degenerative injuries in the elderly and acute injuries in athletes?

In fact. Articular cartilage is regenerated in both young and old. This is influenced by the regenerative capacity of tissues, which, although age-related, is also achieved in the elderly.

What does the treatment or procedure itself depend on?

It is a treatment that is performed in the entire operating room with a single surgical intervention and under local anaesthesia. It consists of extracting the bone marrow, a type of blood that is inside the bones, and treating it in a small laboratory located in the same operating room, then transplanting it to the knee through endoscopy after a simple previous procedure on the knee joint. the affected area.

Can this intervention avoid the placement of a prosthesis?

The idea is to prevent the progression of cartilage disease and no need for a prosthesis to be fitted.

Will the patient be able to continue exercising and lead a normal life? Can these lesions regress with treatment?

In the cases of the athletes, we have achieved complete regeneration of the injury, and we have achieved complete reintegration of their usual sports practice. In cases of degenerative injury we have been able to reduce the intensity of the pain by a very large percentage.

Are growth factors (PRP) and stem cells the same? What is the difference between them?

The two products should not be confused at any point, they have nothing in common. Growth factors, proteins and cytokines (molecules) are released by platelets when they are activated in the clotting process due to injury or trauma. Platelets are mature, developed cells that do not in themselves have any ability to regenerate. They only contribute to the coagulation process and the start of regeneration. It can be easily obtained and isolated from blood by venipuncture and simple centrifugation.

However, progenitor cells (stem cells) are immature cells and the origin of all groups of cells found in the human body and in any living organism. With this, they have the greatest ability to repair and regenerate all damaged tissues and organs, as well as enormous therapeutic potential for any diseases. It is not easy to obtain and we find it mostly in various sources, such as bone marrow and umbilical cord, among others.

Dr. Daniel Martin Casula

Inquiries Address:

• Diagonal Clinic: Sant Mateo, 26, 08950, Barcelona. Phone: 34931 549026

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